Yes you can. I have been doing this for the past 6 months and IMHO sounds great to FOH. The other thing I like is that I can now independently control my stage volume. I use 2 Marshall 1936 2x12 cabinets with 1 each side of the stage and control the volume for each from a Fryette 5050 power amp. It's the best live setup I have ever used and sounds great too.
-P